One PerioChip® is placed into each periodontal pocket of 5mm or more in depth. Up to eight PerioChip® may be inserted in a single visit. PerioChip® does not need to be removed since it biodegrades completely. In the unlikely event that the PerioChip® dislodges (in the two pivotal clinical trials, only 8 chips were reported lost), several actions are recommended, depending on the number of days after insertion of the PerioChip®. If the PerioChip® dislodges 7 days or more after placement, the dentist should consider the subject to have received a full course of treatment. If the PerioChip® dislodges within 48 hours after placement, a new PerioChip®should be inserted. If the PerioChip® dislodges more than 48 hours after placement, the dentist should not replace the PerioChip®, but simply reevaluate the patient after 3 months and insert a new PerioChip® if the pocket depth has not been reduced to less than 5 mm.