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IMPORTANT SAFETY INFORMATION
PerioChip® should not be used in any patient who has a known sensitivity to chlorhexidine. Anaphylaxis, as well as serious allergic reactions, have been reported during postmarketing use with dental products containing chlorhexidine.
Clinical and microbiological effects of sustained release chlorhexidine in periodontal pockets
Previous studies have shown that a 3-day exposure of the pocket flora to the sustained release of chlorhexidine significantly reduced the relative...
Sustained Local Delivery of Chlorhexidine in the Treatment of Periodontitis: A Multi-Center Study
The safety and efficacy of a degradable, subgingivally placed drug delivery system containing 2.5 mg chlorhexidine (CHX) were evaluated in a ...
Probing Depth Changes Following 2 Years of Periodontal Maintenance Therapy Including Adjunctive Controlled
Multicenter clinical trials have established that the adjunctive use of the...
An in vivo study of the chlorhexidine release profile of the PerioChip™ in the gingival crevicular fluid, plasma and urine
The release profile of chlorhexidine from the PerioChip (Chip), a biodegradable local delivery system that contains 2.5 mg of chlorhexidine gluconate (CHX) in...
Effect of a subgingival chlorhexidine chip on the clinical parameters and the levels of alkaline phosphatase activity
The main therapeutic approaches for inflammatory periodontal diseases include...
Adjunctive Use of a Subgingival Controlled-Release Chlorhexidine chip Reduces Probing Depth
The present studies evaluated the efficacy of a controlled-release biodegradable...
Use of a Biodegradable Chlorhexidine Chip in the Treatment of Adult Periodontitis: Clinical and Radiographic Findings
Previous multi-center trials demonstrated the efficacy of a biodegradable chlorhexidine-gelatin chip (CHX) in reducing probing depth in patients with...